Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL50488 | 94311 | Portugal | 2004 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC+ NVP | 52 |
| 2 | AZT+ DDI+ NVP | 65 |
| 3 | None | 47 |
| 4 | DDI+ 3TC+ IDV+ RTV | 84 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82T, I84V, L90M | I13V, K14R, I15V, K20I, E35D, M36I, R41K, C67F, H69K, A71V, L89I |
| >94311| codons 1-99 PQITLWQRPLVTVRVGGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVRQYD QILIEIFGKKVIGTVLVGPTPTNVIGRNIMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74V, M184V, T215Y | K103N | V35T, K43R, V60I, A98S, K122E, D123S, I135T, K173I, Q174K, D177E, D192DN, T200A, E203D, Q207K, R211N, V245Q, E248D, D250E, A272P, T286A, V292I, I293V, E297T, D320E, D324E, I329V, Q334P |
| >94311| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTELEREGKISKIGPENPYNTPI FAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHPSGLKKNKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPEIVI YQYVDDLYVGSNLEIGQHRAKIDELRKHLLNWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEIVPLTTEAE LELAENREILKEPVHGVYYEPSKELIAEVQKQGPG |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |