Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL50270 | 93684 | Portugal | 2004 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC+ TDF | 56 |
| 2 | DDI+ 3TC+ TDF | 30 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65KR | V35T, V60I, K122E, D123DN, I135T, E138A, I142V, S162SN, K166KR, K173IL, Q174K, V179VI, Q197E, I202V, Q207A, R211S, F214L, V245M, D250E, A272P, K277R, T286A, E291D, I293V, P294T, L295LM, K311KR, E312D |
| >93684| codons 1-334 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI FAIKRKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSTNNATPGVRYQYNVLPQGWKGSPAIFQNSMTRILEPFRLKNPDIII YQYMDDLYVGSDLEIGEHRTKVEELRAHLLSWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIMLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDVVTMTEEAE LELAENREILRDPVHGVYYDPSKDLIAEIQKQGQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, I13V, G16GE, E35D, M36I, N37D, K45R, R57K, L63S, H69K, L89M |
| >93684| codons 1-99 PQITLWQRPIVTVKIEGQLKEALLDTGADDTVLEDIDLPGRWKPRMIGGIGGFIKVKQYD QISIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |