Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL49992 | 92981 | Portugal | 2004 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC+ EFV | 154 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V | V75L | V106M | V179D | T27A, V35T, T39E, K103R, K122E, D123S, I135T, K173A, T200A, Q207E, R211K, F214L, V245Q, K277R, L283LI, T286TA, V292VI, I293V, P294T, E297D, I326V |
| >92981| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLAEEKIKALTEICEELEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLLDFRELNKRTQDFWEVQLGIPHPAGLKKRKSMTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPDIDI YQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLIRGAKALTEIVTLTDEAE LELAENREILKEPVHGVYYDPSKDLVAEIQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, M36L, N37S, L63P, H69K, L89M, I93L |
| >92981| codons 1-99 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEELSLPGRWKPKMIGGIGGFIKVRQYD QIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |