<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PL49992 92981 Portugal 2004 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 AZT+ 3TC+ EFV 154

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, M36L, N37S, L63P, H69K, L89M, I93L  
>92981| codons 1-99
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEELSLPGRWKPKMIGGIGGFIKVRQYD
QIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, M184V V75L V106M V179D T27A, V35T, T39E, K103R, K122E, D123S, I135T, K173A, T200A, Q207E, R211K, F214L, V245Q, K277R, L283LI, T286TA, V292VI, I293V, P294T, E297D, I326V  
>92981| codons 1-333
PISPIETVPVKLKPGMDGPKVKQWPLAEEKIKALTEICEELEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLLDFRELNKRTQDFWEVQLGIPHPAGLKKRKSMTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPDIDI
YQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLIRGAKALTEIVTLTDEAE
LELAENREILKEPVHGVYYDPSKDLVAEIQKQG

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005