<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PL49853 92544 Portugal 2004 HIV1 A Plasma None

Treatment History
Order Regimen Weeks
1 AZT+ 3TC+ ABC 92

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, M184V T215I, K219E     S3R, K11S, V35T, T39N, K64KN, K122E, D123N, A158S, K173T, Q174K, D177E, I178M, T200A, Q207A, R211S, V245E, A272P, K281KR, E291D, I293V, P294PT, L295M, E297KQ, E312D  
>92544| codons 1-333
PIRPIETVPVSLKPGMDGPKVKQWPLTEEKIKALTEICNEMEKEGKISKIGPENPYNTPV
FAINKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPSIFQSSMTKILEPFRTKNPEMVI
YQYVDDLYVGSDLEIGQHRAKIEELRAHLLSWGFITPDEKHQKEPPFLWMGYELHPDKWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGTKALTDVVTMTQEAE
LELAENREILKDPVHGVYYDPSKDLIAEIQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, I13V, G16E, E35D, M36I, R41K, K45R, L63Q, H69K, L89I  
>92544| codons 1-99
PQITLWQRPVVTVKIEGQLKEALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVRQYD
QIQIEICGKKAIGTVLVGPTPVNIIGRNILTQIGCTLNF

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005