Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL49853 | 92544 | Portugal | 2004 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC+ ABC | 92 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10V, I13V, G16E, E35D, M36I, R41K, K45R, L63Q, H69K, L89I |
| >92544| codons 1-99 PQITLWQRPVVTVKIEGQLKEALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVRQYD QIQIEICGKKAIGTVLVGPTPVNIIGRNILTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V | T215I, K219E | S3R, K11S, V35T, T39N, K64KN, K122E, D123N, A158S, K173T, Q174K, D177E, I178M, T200A, Q207A, R211S, V245E, A272P, K281KR, E291D, I293V, P294PT, L295M, E297KQ, E312D |
| >92544| codons 1-333 PIRPIETVPVSLKPGMDGPKVKQWPLTEEKIKALTEICNEMEKEGKISKIGPENPYNTPV FAINKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPSIFQSSMTKILEPFRTKNPEMVI YQYVDDLYVGSDLEIGQHRAKIEELRAHLLSWGFITPDEKHQKEPPFLWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGTKALTDVVTMTQEAE LELAENREILKDPVHGVYYDPSKDLIAEIQKQG |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |