Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL49358 | 91289 | Portugal | 2003 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC+ IDV | 104 |
| 2 | None | 252 |
| 3 | DDI+ 3TC+ EFV | 21 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184MIV | T215E | K103N | V179E | E28K, V35T, K43R, V60VI, W88C, A98S, K122E, D123S, I135T, S163C, K173L, Q174K, D177E, I178M, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D324E, I329V |
| >91289| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTKEKIKALTEICTEMEREGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFCEVQLGIPHPSGLKKNKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSCMTKILEPFRLKNPEMEI YQYVDDLYVGSDLEIGQHRAKIEELRKHLLSWGFETPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTAEAE LELAENREILKEPVHGVYYDPSKELIAEVQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, I13V, K14R, K20I, E35D, M36I, R41K, H69K, K70KR, V82I, L89M |
| >91289| codons 1-98 PQITLWQRPIVTVRIGGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKRAIGTVLVGPTPINIIGRNMLTQIGCTLN |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |