Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL48121 | 87876 | Portugal | 2003 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC+ IDV | 69 |
| 2 | AZT+ 3TC+ NFV | 165 |
| 3 | AZT+ 3TC+ EFV | 49 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, T215Y | Y188L | V21I, V35T, K43R, V60I, A98S, V106VI, K122E, D123S, I135T, K173I, Q174K, D177E, I178L, G196E, T200A, E204D, Q207K, R211S, V245Q, E248D, K249R, D250E, A272P, T286A, E297R |
| >87876| codons 1-320 PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTEICTELEREGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSITVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPELVI YQYVDDLLVGSDLEIEQHRAKIEDLRKHLLSWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDRESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVIPLTREAE LELAENREILKEPVHGVYYD |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | L10I, I13V, K14R, L19I, K20IV, E35D, M36I, N37NT, R41K, I62V, I66F, H69K, A71V, V82I, Q92K |
| >87876| codons 1-99 PQITLWQRPIVTVRIGGQIVEALLDTGADDTVLEDITLPGKWKPKMIGGIGGFIKVRQYD QVLIEFCGKKVIGTVLVGPTPINIIGRNLMTKIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |