<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PL48045 87649 Portugal 2003 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 DDI+ 3TC+ EFV 31

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K103N, V106M   V35T, T39D, S48T, V60I, W88S, D121H, K122E, I135X, E138A, T139A, K173A, Q174K, I178L, V179I, T200A, Q207E, R211K, F214FL, V245Q, E248D, A272P, K275R, Q278H, K281KR, L283I, T286A, E291D, V292I, I293V, V317VA, I329V  
>87649| codons 1-334
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICDEMEKEGKITKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFSEVQLGIPHPAGLKKNKSMTVLDVGDAYFSVPL
HEDFRKYTAFTIPSXNNAAPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPDLII
YQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIRVKHLCRLIRGAKALTDIVPLTEEAE
LELAENREILKEPVHGAYYDPSKDLIAEVQKQGQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, M36I, R41K, L63LP, H69K, K70R, V82I, L89M, I93L  
>87649| codons 1-99
PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QIPIEICGKRAIGTVLVGPTPINIIGRNMLTQLGCTLNF

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005