Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL48045 | 87649 | Portugal | 2003 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI+ 3TC+ EFV | 31 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, M36I, R41K, L63LP, H69K, K70R, V82I, L89M, I93L |
| >87649| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QIPIEICGKRAIGTVLVGPTPINIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K103N, V106M | V35T, T39D, S48T, V60I, W88S, D121H, K122E, I135X, E138A, T139A, K173A, Q174K, I178L, V179I, T200A, Q207E, R211K, F214FL, V245Q, E248D, A272P, K275R, Q278H, K281KR, L283I, T286A, E291D, V292I, I293V, V317VA, I329V |
| >87649| codons 1-334 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICDEMEKEGKITKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFSEVQLGIPHPAGLKKNKSMTVLDVGDAYFSVPL HEDFRKYTAFTIPSXNNAAPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPDLII YQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIRVKHLCRLIRGAKALTDIVPLTEEAE LELAENREILKEPVHGAYYDPSKDLIAEVQKQGQ |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |