Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL46739 | 84133 | Portugal | 2003 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC+ IDV | 25 |
| 2 | DDI+ TDF+ EFV | 16 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65KR, M184MV | L100LI, K103KN | V108VIM, P225PH | V35T, K43R, V60I, K64R, V90I, A98S, K122E, D123S, S162A, K173KR, Q174E, D177E, I195K, T200A, V245Q, E248A, D250E, A272P, V276IT, K277KR, T286A, E291D, V292I, I293V, E297AT, D320E, D324E, I329V, Q334P |
| >84133| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEREGKISKIGPENPYNTPI FAIRRKDSTKWRKLVDFRELNKRTQDFWEIQLGIPHPSGIKKNKSVTMLDVGDAYFSVPL DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRRENPEIVI YQYVDDLYVGSDLEKGQHRAKIEELRQHLLRWGFTTPDKKHQKEHPFLWMGYELHPDKWT VQPIQLPAKESWTVNDIQKLVGKLNWASQIYPGIKTRQLCKLLRGAKALTDIVPLTTEAE LELAENREILKEPVHGVYYEPSKELIAEVQKQGPG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, K20I, E35D, M36I, R41K, H69K, V82I, L89M |
| >84133| codons 1-99 PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |