<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PL46148 82690 Portugal 2003 HIV1 CRF02_AG Plasma None

Treatment History
Order Regimen Weeks
1 D4T+ DDI+ IDV 65
2 None 91
3 AZT+ 3TC+ EFV 105

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14KT, G16E, K20I, M36I, N37D, R41K, H69K, K70R, I72IV, L89M  
>82690| codons 1-99
PQITLWQRPLVTVTIEGQLIEALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKRAVGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
    K103N   V35M, E36D, T39A, E40ED, I135T, K173I, Q174K, D177E, T200A, I202IV, Q207K, R211NS, V245Q, E248D, D250E, S251SR, T286A, E291D, V292I, I293V, P294A, K311R, S322T, I326V  
>82690| codons 1-334
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALMDICADMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPEIVI
YQYMDDLYVGSDLEIGQHRAKVEELRKHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKERWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVALTEEAE
LELAENREILREPVHGVYYDPTKDLVAEIQKQGQ

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005