<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PL46060 82450 Portugal 2003 HIV1 G Plasma None

Treatment History
Order Regimen Weeks
1 AZT+ 3TC+ EFV 29

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V T215TI L100LI, K103N   I31IL, K32I, V35T, E36ED, K43R, K49KR, V60I, V90VI, A98S, K122E, D123S, I135R, S162H, K173M, D177E, T200A, Q207K, R211S, H221HY, V245Q, E248D, D250E, A272P, T286A, V292I, I293V, E297A, D320E, I329V, Q330P, K331N, Q334L  
>82450| codons 1-335
PISPIETVPVKLKPGMDGPKVKQWPLTEEKLIALTDICTEMEREGKISRIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEIQLGIPHPSGIKKNKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSRNNETPGIRYQYNVLPQGWKGSPAIFQHSMTKILEPFRMQNPEIVI
YQYVDDLYVGSDLEIGQHRAKIEELRKHLLSWGFITPDKKYQKEPPFLWMGYELHPDKWT
VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEIVPLTAEAE
LELAENREILKEPVHGVYYEPSKDLIAEVPNQGLG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12TKPQ, I13V, K14KR, Q18QR, K20I, E35D, M36I, R41K, R57RK, L63LP, I64IL, C67CY, H69K, P79PH, V82I, L89M  
>82450| codons 1-99
PQITLWQRPLVQVRIGGRLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
QIPLEIYGKKAIGTVLVGHTPINIIGRNMLTQIGCTLNF

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005