Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL46060 | 82450 | Portugal | 2003 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC+ EFV | 29 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | T215TI | L100LI, K103N | I31IL, K32I, V35T, E36ED, K43R, K49KR, V60I, V90VI, A98S, K122E, D123S, I135R, S162H, K173M, D177E, T200A, Q207K, R211S, H221HY, V245Q, E248D, D250E, A272P, T286A, V292I, I293V, E297A, D320E, I329V, Q330P, K331N, Q334L |
| >82450| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTEEKLIALTDICTEMEREGKISRIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEIQLGIPHPSGIKKNKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSRNNETPGIRYQYNVLPQGWKGSPAIFQHSMTKILEPFRMQNPEIVI YQYVDDLYVGSDLEIGQHRAKIEELRKHLLSWGFITPDKKYQKEPPFLWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEIVPLTAEAE LELAENREILKEPVHGVYYEPSKDLIAEVPNQGLG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12TKPQ, I13V, K14KR, Q18QR, K20I, E35D, M36I, R41K, R57RK, L63LP, I64IL, C67CY, H69K, P79PH, V82I, L89M |
| >82450| codons 1-99 PQITLWQRPLVQVRIGGRLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD QIPLEIYGKKAIGTVLVGHTPINIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |