Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL45675 | 81585 | Portugal | 2003 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDI | 34 |
| 2 | AZT+ 3TC | 143 |
| 3 | D4T+ 3TC+ NVP | 201 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, K20I, E35D, M36I, R41K, R57K, L63P, C67E, H69K, V82I, L89M |
| >81585| codons 1-99 PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD QIPIEIEGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V, T215F | Y181C, G190A | A98G | K20R, V21I, V35T, K49KR, V60I, K101Q, K122E, D123S, I135V, K166R, K173A, Q174R, D177E, I178M, T200A, Q207E, R211K, V245Q, E248N, S251I, A272P, K277R, E291D, V292I, E297A, L301M, D324E, I329V |
| >81585| codons 1-332 PISPIETVPVKLKPGMDGPRIKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPGGLQKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRARNPEMVI CQYVDDLYVASDLEIGQHRAKIEELREHLLKWGFFTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPNKDIWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIIPLTAEAE MELAENREILKEPVHGVYYDPSKELIAEVQKQ |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |