Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL45175 | 80399 | Portugal | 2003 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 47 |
| 2 | AZT+ DDI | 335 |
| 3 | D4T+ 3TC+ EFV | 59 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, I13V, K14KR, G16E, K20R, E35D, M36I, R41K, R57K, L63S, H69K, K70R, L89M |
| >80399| codons 1-99 PQITLWQRPIVTVRIEGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD QISIEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70KR, M184V, L210W, T215F | K219E | K103KN, Y181YC | V35T, T39A, V60I, V118I, K122E, D123S, I135K, E169D, K173A, Q174K, D177E, I178L, V179I, Q207A, R211DN, F214FL, L228H, V245R, T286A, E291D, I293V, P294T, V317A, K331N |
| >80399| codons 1-334 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICAELEKEGKISKIGPENPYNTPI FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSIPL DESFRKYTAFTIPSKNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRAKNPELII CQYVDDLYVGSDLEIGQHRTKIEELRAHLWNWGLFTPDEKHQKEPPFHWMGYELHPDKWT VQPIRLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDVVTLTEEAE LELAENREILKEPVHGAYYDPSKDLIAEIQNQGQ |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |