Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL45122 | 80255 | Portugal | 2003 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC+ ABC | 58 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Q151M, M184V | V75I, F77L, F116Y | V21I, V35T, E40D, V60I, A98S, K122E, D123S, S163T, K173T, Q174K, D177E, T200A, R211S, V245Q, E248A, D250E, A272P, Q278H, T286A, E291D, V292I, I293IV, E297A, A304E, I329V, K331N |
| >80255| codons 1-335 PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTEICTDMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLIDLRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYYSVPL DESFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQSTMTKILEPFRTKNPEIVI YQYVDDLYVGSDLEIGQHRAKIEELRQHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPAKESWTVNDIQKLVGKLNWASQIYPGIKVKHLCKLLRGAKALTDIVPLTAEAE LELEENREILKEPVHGVYYDPSKDLIAEVQNQGQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, I15V, K20I, E35D, M36I, R41K, L63P, H69K, T74A, L89M, I93L |
| >80255| codons 1-99 PQITLWQRPLVTVRVGGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QIPIEICGKKAIGAVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |