<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PL45122 80255 Portugal 2003 HIV1 G Plasma None

Treatment History
Order Regimen Weeks
1 AZT+ 3TC+ ABC 58

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
Q151M, M184V V75I, F77L, F116Y     V21I, V35T, E40D, V60I, A98S, K122E, D123S, S163T, K173T, Q174K, D177E, T200A, R211S, V245Q, E248A, D250E, A272P, Q278H, T286A, E291D, V292I, I293IV, E297A, A304E, I329V, K331N  
>80255| codons 1-335
PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTEICTDMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLIDLRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYYSVPL
DESFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQSTMTKILEPFRTKNPEIVI
YQYVDDLYVGSDLEIGQHRAKIEELRQHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPAKESWTVNDIQKLVGKLNWASQIYPGIKVKHLCKLLRGAKALTDIVPLTAEAE
LELEENREILKEPVHGVYYDPSKDLIAEVQNQGQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, I15V, K20I, E35D, M36I, R41K, L63P, H69K, T74A, L89M, I93L  
>80255| codons 1-99
PQITLWQRPLVTVRVGGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QIPIEICGKKAIGAVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005