<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PL44981 79914 Portugal 2003 HIV1 G Plasma None

Treatment History
Order Regimen Weeks
1 D4T+ 3TC+ IDV 77

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V       V35T, T39L, K43R, V60I, A98S, K122E, D123S, I135T, K173V, Q174K, D177E, E194Q, G196E, T200A, R211S, V245Q, E248ED, D250E, A272P, T286A, E291D, V292I, I293V, P294PQ, E297AT, L301M, D320E, D324E, I329V, K331N, Q334P  
>79914| codons 1-335
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICLEMEREGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRVKNPEIVI
YQYVDDLYVGSDLQIEQHRAKIEELRQHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVQLTTEAE
MELAENREILKEPVHGVYYEPSKELIAEVQNQGPG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, K20I, E35D, M36I, N37D, R41K, H69K, K70R, V82I, L89M  
>79914| codons 1-99
PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKRAIGTVLVGPTPINIIGRNMLTQIGCTLNF

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005