Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL44924 | 79756 | Portugal | 2003 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | Unknown | 52 |
| 2 | D4T+DDI+LPV+NVP | 82 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T215Y | K219N | K103N, Y181C | V35T, T39A, K43R, V60I, A98S, K101KR, K122E, D123S, I135V, S162AD, K173R, Q174K, T200A, E203K, Q207E, R211RKNS, V245Q, E248D, D250E, A272P, T286A, V292I, I293V, E297A, I329V |
| >79756| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICAELEREGKISKIGPENPYNTPI FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLRKNKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQDSMTKILEPFRRKNPDIVI CQYMDDLYVGSDLEIGQHRAKIKELREHLLSWGFYTPDNKHQKEPPFLWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEIVPLTAEAE LELAENREILKEPVHGVYYDPSKDLIAEVQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, L90M | F53L | I13V, I15IV, K20I, E35D, M36I, N37ND, R41K, I62V, L63P, H69K, K70KR, A71V, T74S, V82I, L89I, Q92QR |
| >79756| codons 1-99 PQITLWQRPLVTVKVGGQLIEALLDTGADDTVLEDIDLPGKWKPKMIGGIGGLVKVRQYD QVPIEICGKRVIGSVLVGPTPINIIGRNIMTRIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |