<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PL44924 79756 Portugal 2003 HIV1 G Plasma None

Treatment History
Order Regimen Weeks
1 Unknown 52
2 D4T+DDI+LPV+NVP 82

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, L90M F53L I13V, I15IV, K20I, E35D, M36I, N37ND, R41K, I62V, L63P, H69K, K70KR, A71V, T74S, V82I, L89I, Q92QR  
>79756| codons 1-99
PQITLWQRPLVTVKVGGQLIEALLDTGADDTVLEDIDLPGKWKPKMIGGIGGLVKVRQYD
QVPIEICGKRVIGSVLVGPTPINIIGRNIMTRIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T215Y K219N K103N, Y181C   V35T, T39A, K43R, V60I, A98S, K101KR, K122E, D123S, I135V, S162AD, K173R, Q174K, T200A, E203K, Q207E, R211RKNS, V245Q, E248D, D250E, A272P, T286A, V292I, I293V, E297A, I329V  
>79756| codons 1-333
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICAELEREGKISKIGPENPYNTPI
FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLRKNKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQDSMTKILEPFRRKNPDIVI
CQYMDDLYVGSDLEIGQHRAKIKELREHLLSWGFYTPDNKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEIVPLTAEAE
LELAENREILKEPVHGVYYDPSKDLIAEVQKQG

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005