Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL44326 | 78321 | Portugal | 2003 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+ 3TC+ IDV | 263 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, L90M | I13V, K14KR, K20I, E35D, M36I, R41K, H69K, V82I, L89M, I93M |
| >78321| codons 1-99 PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEDINLPGKWKPKIIGGIGGFVKVRQYD QILIEICGKKAIGTVLVGPTPINIIGRNMMTQMGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | V35T, K43KR, K49KR, V60VI, A98S, K122E, D123N, I135T, T165I, K173I, Q174K, D177E, T200A, Q207K, R211S, F214L, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, V317VA, D324E, I329V |
| >78321| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEREGKISRIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMIKILEPFRIKNPEIVI YQYVDDLYVGSDLEIGQHRAKIEELRKHLLSWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTAEAE LELAENREILKEPVHGAYYDPSKELIAEVQKQG |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |