Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL44104 | 77796 | Portugal | 2003 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDI+ DDC+ SQV | 78 |
| 2 | D4T+ 3TC+ NVP | 78 |
| 3 | D4T+ 3TC+ EFV | 144 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K103N | A98AG, V179VE, P225PH, K238T | K20KR, E28EK, V35T, E40ED, V60I, V90VI, K122E, D123N, I135L, S162A, K173T, D177E, G196GR, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D320DE, D324E, I329V |
| >77796| codons 1-333 PISPIETVPVKLKPGMDGPRVKQWPLTKEKIKALTEICTDMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEIQLGIPHPGGLKKNKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTQNPEIEI YQYMDDLYVGSDLEIRQHRAKIEELRKHLLSWGFTTPDKKHQKEHPFLWMGYELHPDTWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTAEAE LELAENREILKEPVHGVYYEPSKELIAEVQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K20I, E35D, M36I, R41K, H69K, K70KR, I72IT, V82I, L89M |
| >77796| codons 1-99 PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKRATGTVLVGPTPINIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |