<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PL43995 101842 Portugal 2004 HIV1 G Plasma None

Treatment History
Order Regimen Weeks
1 D4T+ DDI+ NVP 83

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41ML, D67DN, T215Y   V106A F227L V35T, K43R, K49KR, V60I, A98S, K122E, D123S, I135T, S162SN, K173I, Q174K, D177E, T200A, R211S, V245Q, E248D, D250E, A272P, T286A, A288G, E291D, V292I, I293V, E297T, D320E, D324E, I329V P157PA
>101842| codons 1-333
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTELEREGKISRIGPENPYNTPI
FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSATVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSAAIFQNSMTKILEPFRIKNPEIVI
YQYMDDLYVGSDLEIGQHRAKIEELRQHLLSWGFYTPDKKHQKEPPLLWMGYELHPDKWT
VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKGLTDIVPLTTEAE
LELAENREILKEPVHGVYYEPSKELIAEVQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10I, I13V, K20I, E35D, M36I, R41K, H69K, K70R, V82I, L89M  
>101842| codons 1-98
PQITLWQRPIVTVKIGGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKRAIGTVLVGPTPINIIGRNMLTQIGCTLN

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005