Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL43995 | 101842 | Portugal | 2004 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+ DDI+ NVP | 83 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, I13V, K20I, E35D, M36I, R41K, H69K, K70R, V82I, L89M |
| >101842| codons 1-98 PQITLWQRPIVTVKIGGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKRAIGTVLVGPTPINIIGRNMLTQIGCTLN |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41ML, D67DN, T215Y | V106A | F227L | V35T, K43R, K49KR, V60I, A98S, K122E, D123S, I135T, S162SN, K173I, Q174K, D177E, T200A, R211S, V245Q, E248D, D250E, A272P, T286A, A288G, E291D, V292I, I293V, E297T, D320E, D324E, I329V | P157PA |
| >101842| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTELEREGKISRIGPENPYNTPI FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSATVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSAAIFQNSMTKILEPFRIKNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELRQHLLSWGFYTPDKKHQKEPPLLWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKGLTDIVPLTTEAE LELAENREILKEPVHGVYYEPSKELIAEVQKQG |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |