Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL43562 | 76535 | Portugal | 2002 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC+ IDV+ SQV | 86 |
| 2 | None | 252 |
| 3 | D4T+ 3TC+ NVP | 128 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, M184V, T215F | K219Q | K101KPQT, K103S, G190A | T7TAP, E28EA, V35T, T39TA, V60I, A98S, D121H, K122E, I135T, K166R, Q174E, D177E, T200A, I202IV, Q207K, R211N, V245Q, E248D, D250E, A272P, T286A, V292I, I293V, E297A, I329V, K331N |
| >76535| codons 1-334 PISPIEPVPVKLKPGMDGPKVKQWPLTAEKIKALTEICAELEKEGKISKIGPENPYNTPI FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLTKSKSVTVLDVGDAYFSVPL HEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKENPEIVI YQYVDDLYVASDLEIGQHRAKVEELRKHLLNWGFFTPDQKHQKEPPFLWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEIVPLTAEAE LELAENREILKEPVHGVYYDPSKDLIAEVQNQGQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82S | I13V, K14R, I15V, K20I, E35D, M36I, R41K, L63P, H69K, A71V, T74S, L89I |
| >76535| codons 1-99 PQITLWQRPLVTVRVGGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVRQYD QIPIEICGKKVIGSVLVGPTPSNIIGRNILTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |