Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL43110 | 75401 | Portugal | 2003 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC+ IDV | 208 |
| 2 | AZT+ 3TC+ NVP | 100 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| K20R, E35D, M36I, N37D, R41K, I62V, L63T, H69K, L89M |
| >75401| codons 1-99 PQITLWQRPLVTIKIGGQLREALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFIKVRQYD QVTIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | A62V | K103N | V35T, T39E, I135T, A158S, K173A, D177E, T200A, K201I, E204K, Q207A, R211RS, P243PS, V245EK, A272P, E291D, I293V, E312N | N54I |
| >75401| codons 1-334 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKISKIGPEIPYNTPV FVIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPSIFQSSMTKILEPFRAQNPEIVI YQYVDDLYVGSDLEIGQHRAIIEKLRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQSIKLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTDVVPLTEEAE LELAENREILKNPVHGVYYDPSKDLIAEIQKQGQ |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |