Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL43077 | 75315 | Portugal | 2002 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDC | 43 |
| 2 | AZT+ 3TC+ NVP | 8 |
| 3 | AZT+ 3TC+ NFV | 224 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, T215F | V21I, T27P, V35T, K43R, A98S, K122E, D123S, I135T, K173N, Q174K, D177E, T200A, Q207K, R211S, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, E297A, P321S, D324E, I329V, K331N, Q332K |
| >75315| codons 1-333 PISPIETVPVKLKPGMDGPKIKQWPLPEEKIKALTEICTELEREGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRNKNPEIVI YQYVDDLYVGSDLEIGQHRAKIEELRKHLLSWGFFTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTAEAE LELAENREILKEPVHGVYYDSSKELIAEVQNKG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, L90M | I13V, K14R, L19I, K20I, E35N, M36I, R41K, K55KR, R57RK, H69K, V82I, L89M |
| >75315| codons 1-99 PQITLWQRPLVTVRIGGQIIEALLDTGADDTVLENINLPGKWKPKLIGGIGGFVRVKQYD QILIEICGKKAIGTVLVGPTPINIIGRNMMTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |