<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
pt-K ptKW18 U.S. 1995 HIV1 B PBMC MMC

Treatment History
Order Regimen Weeks
1 IDV 18

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, V82F L24I N37S, I64V, I93L E65I
>ptKW18| 8 | codons 1-99 | clone 8
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILVEICGHKAIGTVLIGPTPFNIIGRNLLTQIGCTLNF
>ptKW18| 7 | codons 1-99 | clone 7
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEISLPGRWKPKIIGGIGGFIKVRQYD
QILVEICGHKAIGTVLIGPTPVYIIGRNLLTQLGCTLNF
>ptKW18| 6 | codons 1-99 | clone 6
PQITLWQRPFVTIKIGGQLKEALIDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILVEICGHKAIGTVLIGPTPFNIIGRNLLTQLGCTLNF
>ptKW18| 5 | codons 1-99 | clone 5
PQITLWQRPLVTIKIGGQLKEALIDTGADDTVLEEMSLPGRWKPKIIGGIGGFIKVRQYD
QILVEICGHKAIGTVLIGPTPFNIIGRNLLTQIGCTLNF
>ptKW18| 4 | codons 1-99 | clone 4
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKIIGGIGGFIKVRQYD
QILVEICGHKAIGTVLIGPTPVYIIGRNLLTQIGCTLNF
>ptKW18| 3 | codons 1-99 | clone 3
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILVEICGHKAIGTVLIGPTPFNIIGRNLLTQIGCTLNF
>ptKW18| 2 | codons 1-99 | clone 2
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILVEICGHKAIGTVLIGPTPFNIIGRNLLTQIGCTLNF
>ptKW18| 1 | codons 1-99 | clone 1
PQITLWQRPLVTIKIGGQLKEALIDTGADDTVLEEMSLPGRWKPKIIGGIGGFIKVRQYD
QILVEICGHKAIGTVLIGPTPVNIIGRNLLTQLGCTLNF
>ptKW18| codons 1-99
PQITLWQRPLVTIKIGGQLKEALIDTGADDTVLEEMSLPGRWKPKIIGGIGGFIKVRQYD
QILVIICGHKAIGTVLVGPTPFNIIGRNLLTQLGCTLNF

References
Author Title Citation
Condra, JH Genetic correlates of in vivo viral resistance to indinavir, a human immunodeficiency virus type 1 protease inhibitor. J Virol, 1996
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005