Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| pt-K | ptKW18 | U.S. | 1995 | HIV1 | B | PBMC | MMC |
Treatment History
| Order | Regimen | Weeks |
| 1 | IDV | 18 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, V82F | L24I | N37S, I64V, I93L | E65I |
| >ptKW18| 8 | codons 1-99 | clone 8 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD QILVEICGHKAIGTVLIGPTPFNIIGRNLLTQIGCTLNF >ptKW18| 7 | codons 1-99 | clone 7 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEISLPGRWKPKIIGGIGGFIKVRQYD QILVEICGHKAIGTVLIGPTPVYIIGRNLLTQLGCTLNF >ptKW18| 6 | codons 1-99 | clone 6 PQITLWQRPFVTIKIGGQLKEALIDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD QILVEICGHKAIGTVLIGPTPFNIIGRNLLTQLGCTLNF >ptKW18| 5 | codons 1-99 | clone 5 PQITLWQRPLVTIKIGGQLKEALIDTGADDTVLEEMSLPGRWKPKIIGGIGGFIKVRQYD QILVEICGHKAIGTVLIGPTPFNIIGRNLLTQIGCTLNF >ptKW18| 4 | codons 1-99 | clone 4 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKIIGGIGGFIKVRQYD QILVEICGHKAIGTVLIGPTPVYIIGRNLLTQIGCTLNF >ptKW18| 3 | codons 1-99 | clone 3 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD QILVEICGHKAIGTVLIGPTPFNIIGRNLLTQIGCTLNF >ptKW18| 2 | codons 1-99 | clone 2 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD QILVEICGHKAIGTVLIGPTPFNIIGRNLLTQIGCTLNF >ptKW18| 1 | codons 1-99 | clone 1 PQITLWQRPLVTIKIGGQLKEALIDTGADDTVLEEMSLPGRWKPKIIGGIGGFIKVRQYD QILVEICGHKAIGTVLIGPTPVNIIGRNLLTQLGCTLNF >ptKW18| codons 1-99 PQITLWQRPLVTIKIGGQLKEALIDTGADDTVLEEMSLPGRWKPKIIGGIGGFIKVRQYD QILVIICGHKAIGTVLVGPTPFNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Condra, JH | Genetic correlates of in vivo viral resistance to indinavir, a human immunodeficiency virus type 1 protease inhibitor. | J Virol, 1996 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |