Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL42361 | 73571 | Portugal | 2002 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+ DDI+ IDV+ RTV | 69 |
| 2 | AZT+ 3TC+ IDV+ RTV | 91 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, V75M, M184V, T215Y | F77FL, K219E | V35T, K43R, K49R, V60I, K82KR, A98S, K122E, D123S, I135T, F171L, K173I, Q174K, D177E, T200A, E203D, Q207K, R211S, L228H, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A | F214Y, D218DY |
| >73571| codons 1-307 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTELEREGKISRIGPENPYNTPI FAIKKKNSTRWRKLMDLRELNRRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPLRIKNPEIVI YQYVDDLYVGSDLEIGQHRAKIDELRKHLLSWGYYTPYEKHQKEPPFHWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTAEAE LELAENR |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, G48V, I54V, V82S | K43T | L10I, I13A, K14R, K20I, E35D, M36I, R41K, I62V, I66F, H69K, T74S, L89I |
| >73571| codons 1-99 PQITLWQRPIVTARIGGQLIEALLDTGADDTVLEDINLPGKWTPKLIVGIGGFVKVRQYD QVLIEFCGKKAIGSVLVGPTPSNIIGRNILTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |