Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL40517 | 69351 | Portugal | 2002 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC | 295 |
| 2 | D4T+ DDI+ IDV | 130 |
| 3 | D4T+ DDI+ NFV | 111 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, T215F | K219Q | V35T, V60I, D123E, S162C, E169D, K173A, Q174K, I178L, E203D, Q207E, R211K, D218E, K223Q, L228H, V245Q, E248D, A272P, E291D, V292I, I293V, P294T, E297T, S322T, I329L |
| >69351| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTELEKEGKISKIGPENPYNTPI FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILDPFRAKNPDLVI YQYMDDLYVGSDLEIGQHRTKIDELREHLLKWGFFTPEQKHQQEPPFHWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTDIVTLTTEAE LELAENREILKEPVHGVYYDPTKDLIAELQKQGQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | L10I, I15V, G17D, K20T, E35D, M36I, R57K, Q61H, L63P, I64V, A71T, I72V, L89M, I93L |
| >69351| codons 1-99 PQITLWQRPIVTIKVGDQLTEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVKQYD HIPVEICGHKTVGTVLVGPTPVNIIGRNMMTQLGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |