Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL40509 | 77525 | Portugal | 2003 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC | 74 |
| 2 | D4T+ DDI+ NFV | 171 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54IL, L90M | I13V, K14R, K20T, E35D, M36I, R41K, I62IV, H69K, A71T, V82I, L89I |
| >77525| codons 1-99 PQITLWQRPLVTVRIGGQLTEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFLKVRQYD QVLIEICGKKTIGTVLVGPTPINIIGRNIMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T215Y | V35T, T39K, K43R, V60I, A98S, K122E, D123S, I135T, A158AS, S162SN, K173I, Q174K, D177E, T200A, Q207K, R211S, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, E297A, I326L, I329V, K331N, Q334L | V276VA |
| >77525| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICKELEREGKISKIGPENPYNTPI FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPSIFQNSMTKILEPFRIKNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELRKHLLSWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKAKQLCKLLRGAKALTDIVPLTAEAE LELAENREILKEPVHGVYYDPSKDLLAEVQNQGLG |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |