Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL39651 | 67522 | Portugal | 2002 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDI | 4 |
| 2 | None | 8 |
| 3 | AZT+ 3TC+ EFV | 21 |
| 4 | AZT+ 3TC+ NFV | 151 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, L90M | I13V, K14R, K20I, E35N, M36I, R41K, K45KR, I62IV, H69K, A71AV, T74S, V82VI, L89I |
| >67522| codons 1-99 PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLENINLPGKWKPRMIGGIGGFVKVRQYD QVLIEICGKKVIGSVLVGPTPINIIGRNIMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V, T215TNSY | K103KN | E6D, V21I, V35T, V60I, A98S, K122E, D123S, I135V, Q174K, D177E, T200A, Q207E, R211S, V245Q, D250DE, V254VI, A272P, T286A, E291D, V292I, I293V, E297A, D320E, D324E, I329V |
| >67522| codons 1-333 PISPIDTVPVKLKPGMDGPKIKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKNKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKKNPEIVI YQYVDDLYVGSDLEIGQHRAKIEELREHLLSWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKESWTINDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTAEAE LELAENREILKEPVHGVYYEPSKELIAEVQKQG |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |