<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PL39457 67024 Portugal 2002 HIV1 F Plasma None

Treatment History
Order Regimen Weeks
1 AZT+ DDC 210

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41ML, K70KR, T215TNSY K219KQ     V35T, K64KN, D123E, S162Y, F171Y, K173AT, Q174K, V179I, T200A, E203EK, Q207AE, R211K, L228LR, V245Q, D250E, A272P, K275Q, K277R, T286A, E291D, V292I, I293V, E297IR, Q334QE  
>67024| codons 1-335
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTELEKEGKISKIGPENPYNTPV
FAINKKDSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPYRTKNPDIII
YQYMDDLYVGSDLEIGQHRAKIKELREHLLKWGFYTPDQKHQKEPPFRWMGYELHPDKWT
VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIQVRQLCKLLRGAKALTDIVPLTREAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGEG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, G17E, E35D, M36I, R57K, Q61H, L89M  
>67024| codons 1-99
PQITLWQRPLVTIKVGEQLKEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVKQYD
HILIEICGHKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005