Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL3890 | 100322 | Portugal | 2004 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+ DDI+ NFV | 61 |
| 2 | 3TC+ TDF+ EFV | 44 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R, K70KR, Q151M, M184MIV | K103N, G190GA | V108VI | P4S, V35K, T39A, S68G, K122KE, I135V, I142V, S162A, K173I, Q174K, D177E, Q207G, R211K, F214L, V245QR, P247PA, T286A, E291D, V292I, I293V, P294T, V317A, S322T | Q222QR |
| >100322| codons 1-335 PISSIETVPVKLKPGMDGPKVKQWPLTEEKIKALKEICAEMEKEGKISKIGPENPYNTPV FAIKRKDGTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTILDVGDAYFSVPL DEDFRKYTAFTIPSVNNETPGVRYQYNVLPMGWKGSPAIFQASMTKILEPFRIKNPEIVI YQYVDDLYVASDLEIGQHRTKIEELRGHLLKWGLTTPDKKHRKEPPFLWMGYELHPDKWT VQPIRLAEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVTLTEEAE LELAENREILKEPVHGAYYDPTKDLIAEIQKQGQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | I13V, K14R, G16E, K20IV, E35A, M36I, P39PS, R41K, H69K, L89I |
| >100322| codons 1-99 PQITLWQRPLVTVRIEGQLVEALLDTGADDTVLEAINLSGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNIMTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |