Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL37933 | 63674 | Portugal | 2002 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDI+ NVP | 26 |
| 2 | DDI+ 3TC+ IDV | 124 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | I15V, G17E, Q18QH, K20IMT, E35D, M36I, I62V, L63P, L89IM |
| >63674| codons 1-99 PQITLWQRPLVTIKVGEHLTEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKAIGTVLVGPTPVNIIGRNMMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184MV, T215*DEY | Y181C | V21I, V35M, K101Q, S162Y, K166KQ, E169AD, K173A, Q174K, E203EK, Q207E, R211K, L228LH, V245Q, E248D, A272P, K277R, T286TA, E291D, V292I, I293V, E297R, P313T, I326V |
| >63674| codons 1-335 PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALMEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLQKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQYSMTQILDPFRAKNPDIVI CQYVDDLYVGSDLEIGQHRTKIKELREHLLKWGFYTPDKKHQKEPPFHWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTREAE LELAENREILKETVHGVYYDPSKDLVAEIQKQGQG |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |