Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL37498 | 95930 | Portugal | 2004 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 99 |
| 2 | D4T+ 3TC+ IDV | 104 |
| 3 | None | 65 |
| 4 | D4T+ 3TC+ IDV | 4 |
| 5 | None | 34 |
| 6 | AZT+ TDF+ LPV | 89 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T215Y | V35T, K49R, D86E, I135V, S162C, E169D, K173A, Q174K, I178L, E203D, Q207A, R211K, V245Q, P247Q, A272P, K281R, E291D, V292I, I293V, P294T, E297T |
| >95930| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQEFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILDPFRAKNPDLVI YQYMDDLYVGSDLEIGQHRTKIDELRAHLLKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLQEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGTKALTDIVTLTTEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, G17D, K20M, E35D, M36I, R57K, Q61H, L89M |
| >95930| codons 1-99 PQITLWQRPLVTIKVGDQLMEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVKQYD HILIEICGHKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |