<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PL37067 100781 Portugal 2004 HIV1 D Plasma None

Treatment History
Order Regimen Weeks
1 AZT+ 3TC 30
2 AZT+ 3TC+ IDV 26
3 AZT+ 3TC+ IDV+ RTV 135

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L19I, L33V, R41K, H69HQ, I93L  
>100781| codons 1-99
PQITLWQRPLVTIKIGGQIKEALLDTGADDTVVEEMNLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGQKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41ML       E6D, K11R, V35T, E42EK, V60I, K122E, D123G, I135V, D177EG, I178IL, Q207EG, R211K, V245EG, D250E, Q278H, T286A, I293IV, D324DE, Q334HY  
>100781| codons 1-335
PISPIDTVPVRLKPGMDGPKVKQWPLTEEKIKALTEICTELKKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEGFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPGLVI
YQYMDDLYVGSDLEIGQHRTKIEELRGHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIGLPEKESWTVNDIQKLVGKLNWASQIYAGIKVKHLCKLLRGAKALTEVVPLTEEAE
LELAENREILKEPVHGVYYDPSKELIAEIQKQGYG

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005