<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PL36354 60210 Portugal 2001 HIV1 A Plasma None

Treatment History
Order Regimen Weeks
1 AZT+ 3TC+ NVP 61
2 D4T+ 3TC+ NVP 69

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K101DEHQ, G190A   E6K, K11T, K20R, V35T, E36A, T39K, K43E, K102KR, K122E, D123S, I135T, I142IV, S162F, K173S, D177E, V179I, T200TA, Q207EG, R211K, F214L, V245Q, A272P, K281R, T286A, E291D, V292I, I293V, P294T, I326V  
>60210| codons 1-334
PISPIKTVPVTLKPGMDGPRVKQWPLTEEKIKALTAICKEMEEEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLQRKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQFSMTKILEPFRSQNPEIII
YQYVDDLYVASDLEIGQHRAKIEELRGHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGAKALTDIVTLTEEAE
LELAENREILKEPVHGVYYDPSKDLVAEIQKQGQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10I, I13V, K14KR, E35D, M36I, R41K, H69K, V77I, L89M  
>60210| codons 1-99
PQITLWQRPIVTVRIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLIGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005