Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL36354 | 60210 | Portugal | 2001 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC+ NVP | 61 |
| 2 | D4T+ 3TC+ NVP | 69 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K101DEHQ, G190A | E6K, K11T, K20R, V35T, E36A, T39K, K43E, K102KR, K122E, D123S, I135T, I142IV, S162F, K173S, D177E, V179I, T200TA, Q207EG, R211K, F214L, V245Q, A272P, K281R, T286A, E291D, V292I, I293V, P294T, I326V |
| >60210| codons 1-334 PISPIKTVPVTLKPGMDGPRVKQWPLTEEKIKALTAICKEMEEEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLQRKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQFSMTKILEPFRSQNPEIII YQYVDDLYVASDLEIGQHRAKIEELRGHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGAKALTDIVTLTEEAE LELAENREILKEPVHGVYYDPSKDLVAEIQKQGQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, I13V, K14KR, E35D, M36I, R41K, H69K, V77I, L89M |
| >60210| codons 1-99 PQITLWQRPIVTVRIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLIGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |