Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL36137 | 97247 | Portugal | 2004 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDI+ SQV | 317 |
| 2 | AZT+ DDI+ RTV+ SQV | 21 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90LIM | I13V, K20I, E35D, M36I, N37ND, R41K, H69K, T74S, V82I, L89IM |
| >97247| codons 1-99 PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGSVLVGPTPINIIGRNMMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, T215Y | E28K, K32KE, V35T, V60I, A98S, K103Q, K122E, D123S, I135T, K173I, Q174K, D177E, T200A, Q207K, R211S, D237N, V245Q, E248D, D250E, A272P, V276I, T286A, E291D, V292I, I293V, E297A, D324E, I329V |
| >97247| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTKEKIEALTEICTELEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKQKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELRKHLLSWGFYTPDKKHQKEPPFLWMGYELHPNKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKIKQLCKLLRGAKALTDIVPLTAEAE LELAENREILKEPVHGVYYDPSKELIAEVQKQG |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |