Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL34326 | 98448 | Portugal | 2004 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC+ IDV | 61 |
| 2 | D4T+ ABC+ NFV | 56 |
| 3 | D4T+ ABC+ EFV+ NFV | 63 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T215Y | V75VL, K219R | K103N, G190GA | V35T, T39TA, K43R, V60I, V90VI, A98S, S117SA, K122E, D123S, I135T, Q174K, T200A, Q207K, H208HY, R211S, D218E, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297AV | S3SG, N54NI |
| >98448| codons 1-315 PIGPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICAELEREGKISKIGPEIPYNTPI FAIKKKNSTKWRKLLDFRELNKRTQDFWEIQLGIPHPSGLKKNKSVTVLDVGDAYFAVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKKNPDIVI YQYMDDLYVASDLEIGQHRAKIEELRKYLLSWGFYTPERKHQKEPPFLWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTVEAE LELAENREILKEPVH |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82M | L24I, Q58E, L89MV | L10I, I13V, K14R, K20I, E35D, M36I, R41K, Q61N, L63T, H69K |
| >98448| codons 1-99 PQITLWQRPIVTVRIGGQLIEALIDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVREYD NITIEICGKKAIGTVLVGPTPMNIIGRNVLTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |