Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL34057 | 96049 | Portugal | 2004 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC+ NFV | 82 |
| 2 | AZT+ DDI+ NVP | 39 |
| 3 | AZT+ TDF+ NVP | 100 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | I13V, I15V, L19T, K20T, E35G, M36I, P39PA, R41K, Q61QH, L63V, I64IV, H69K, A71V, T74S, L89I, I93L |
| >96049| codons 1-99 PQITLWQRPLVTVKVGGQTTEALLDTGADDTVLEGINLAGKWKPKMIGGIGGFIKVRQYD HIVVEICGKKVIGSVLVGPTPVNIIGRNIMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R, T215F | D67T, K219E | K101E, Y181C, G190A | V8I, V35T, T39D, V60I, T69N, K102Q, V118I, D121H, K122E, I135RT, I142V, S162SN, K166R, D177E, T200A, Q207E, R211K, F214L, V245H, E248D, D250E, A272P, K277R, T286A, E291D, V292I, I293V, E300Q | P9PL |
| >96049| codons 1-333 PISPIETILVKLKPGMDGPKVKQWPLTEEKIKALTEICDEMEKEGKISKIGPENPYNTPI FAIKKKTSNRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEQKKSVTVLDVGDAYFSIPL HEDFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQNSMTRILEPFRKQNPEIVI CQYMDDLYVASDLEIGQHRAKIEELREHLLKWGLFTPDEKHQKEPPFLWMGYELHPDKWT VQPIHLPDKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAQ LELAENREILKEPVHGVYYDPSKDLIAEIQKQG |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |