Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL33730 | 76228 | Portugal | 2002 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | Unknown | 52 |
| 2 | AZT+DDI+IDV+RTV | 80 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82F | L10I, I13V, K14R, K20I, E35D, M36I, R41K, K45Q, H69K, L89M |
| >76228| codons 1-99 PQITLWQRPIVTVRIGGQLIEALLDTGADDTVLEDINLPGKWKPQMIGGIGGFVKVRQYD QILIEICGKKAIGTVLVGPTPFNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T215F | G190A | V21I, T27S, V35T, K43R, V60I, A98S, K122E, D123S, I135T, S162SN, R172RK, K173M, Q174K, D177E, T200A, Q207K, R211S, F214L, V245Q, E248D, D250E, A272P, T286A, E297K, Q334L | E312~, Y318V |
| >76228| codons 1-335 PISPIETVPVKLKPGMDGPKIKQWPLSEEKIKALTEICTEMEREGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQNSMTKILEPFKMKNPEIVI YQYMDDLYVASDLEIGQHRAKIEELRKHLLSWGLFTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVIPLTKEAE LELAENREILK~PVHGVVYDPSKDLIAEIQKQGLG |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |