Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL31998 | 100467 | Portugal | 2004 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC+ NVP | 60 |
| 2 | D4T+ DDI+ IDV+ RTV | 174 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70KE | K103N | K20R, V35T, K43R, V60I, A98S, K122E, D123S, K173R, Q174K, D177E, I195K, T200A, I202IV, R211K, F214L, K238S, V245Q, E248D, D250E, A272P, V276I, T286A, E291D, V292I, I293V, E297A, D320E, D324E, I329V, Q334P |
| >100467| codons 1-335 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICTEMEREGKISKIGPENPYNTPI FAIKKKDSTEWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKNKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRRKNPEIVI YQYMDDLYVGSDLEKGQHRAKVEELRQHLLKWGLTTPDKKHQKEPPFLWMGYELHPDSWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKIKQLCKLLRGAKALTDIVPLTAEAE LELAENREILKEPVHGVYYEPSKELIAEVQKQGPG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46MV | I13V, K14R, K20I, E35D, M36I, R41K, I62IV, H69K, V82I, L89IM |
| >100467| codons 1-99 PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEDINLPGKWKPKVIGGIGGFIKVRQYD QVLIEICGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |