<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PL31998 100467 Portugal 2004 HIV1 G Plasma None

Treatment History
Order Regimen Weeks
1 AZT+ 3TC+ NVP 60
2 D4T+ DDI+ IDV+ RTV 174

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K70KE   K103N   K20R, V35T, K43R, V60I, A98S, K122E, D123S, K173R, Q174K, D177E, I195K, T200A, I202IV, R211K, F214L, K238S, V245Q, E248D, D250E, A272P, V276I, T286A, E291D, V292I, I293V, E297A, D320E, D324E, I329V, Q334P  
>100467| codons 1-335
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICTEMEREGKISKIGPENPYNTPI
FAIKKKDSTEWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKNKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRRKNPEIVI
YQYMDDLYVGSDLEKGQHRAKVEELRQHLLKWGLTTPDKKHQKEPPFLWMGYELHPDSWT
VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKIKQLCKLLRGAKALTDIVPLTAEAE
LELAENREILKEPVHGVYYEPSKELIAEVQKQGPG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  M46MV I13V, K14R, K20I, E35D, M36I, R41K, I62IV, H69K, V82I, L89IM  
>100467| codons 1-99
PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEDINLPGKWKPKVIGGIGGFIKVRQYD
QVLIEICGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005