Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL31915 | 79867 | Portugal | 2003 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC+ NVP | 13 |
| 2 | AZT+ 3TC+ NVP+ D4T+ ABC+ IDV | 21 |
| 3 | D4T+ ABC+ IDV+ DDI | 95 |
| 4 | D4T+ ABC+ IDV+ RTV | 39 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V11VI | L10V, I13V, K14R, G16E, K20I, M36I, R41K, I64IV, H69K, K70R, I72V, L89M | P1PS |
| >79867| codons 1-99 SQITLWQRPVITVRIEGQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QILVEICGKRAVGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184MV | K103N | V35KT, E36D, T39TA, W88C, K122Q, I135T, I142V, S162A, K173KI, Q174EK, D177E, T200A, Q207E, R211K, F214L, V245Q, A272P, V276I, K277R, T286A, E291D, V292VI, I293V, P294T, S322T, I329IV | P157PS, F160FL |
| >79867| codons 1-334 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTDICAEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFCEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DQDFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSSAILQASMTKILEPFRIKNPEIVI YQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKIRQLCKLLRGAKALTDIVTLTEEAE LELAENREILKEPVHGVYYDPTKDLIAEVQKQGQ |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |