Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL30686 | 101546 | Portugal | 2004 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ IDV+ RTV | 95 |
| 2 | AZT+ DDI | 165 |
| 3 | AZT+ 3TC+ IDV+ RTV | 156 |
| 4 | DDI+ TDF+ EFV | 82 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65KR, L74LV | K103N, Y181C | A98AG, V179E | V35T, V60VI, K122E, D123S, I135M, K173T, Q174K, D177E, T200A, Q207K, R211S, V245Q, E248DN, A272P, T286A, E291D, V292I, I293V, E297A, A304E, D320E, D324E, I329V |
| >101546| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI FAIKRKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPGGLKKNKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSMNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEIEI CQYMDDLYVGSDLEIGQHRAKIEELRKHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPNKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTAEAE LELEENREILKEPVHGVYYEPSKELIAEVQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, I15V, K20I, E35D, M36I, R41K, I64IM, H69K, V82I, L89M |
| >101546| codons 1-99 PQITLWQRPLVTVRVGGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILMEICGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |