Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL30594 | 104269 | Portugal | 2004 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+ DDI+ NVP+ NFV | 288 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, Q151M, T215FY | F116Y, K219Q | Y181C | V35T, V60I, T69TA, A98S, K122E, D123S, I135V, M164L, I167IV, K173I, Q174K, D177E, T200A, L205F, Q207A, H208Y, R211RS, D218E, L228LH, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D324E, I329V, G333E, Q334E |
| >104269| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI FAIKKKNSARWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYYSVPL DESFRKYTAFTIPSVNNETPGIRYQYNVLPMGWKGSPAIFQSSLTKVLEPFRIKNPEIVI CQYMDDLYVGSDLEIGQHRAKIEEFRAYLLSWGFYTPEQKHQKEPPFHWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTAEAE LELAENREILKEPVHGVYYDPSKELIAEVQKQEEG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V | L89V | T12TI, I13A, K14R, L19P, K20I, E35D, M36I, N37D, R41K, H69K, V82I |
| >104269| codons 1-99 PQITLWQRPLVIARIGGQPIEALLDTGADDTVLEDIDLPGKWKPKLIGGIGGFVKVRQYD QILIEICGKKAIGTVLVGPTPINIIGRNVLTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |