Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL29090 | 97083 | Portugal | 2004 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDI | 126 |
| 2 | AZT+ DDI+ D4T+ 3TC+ IDV | 21 |
| 3 | AZT+ DDI+ D4T+ 3TC+ NFV | 82 |
| 4 | D4T+ 3TC+ NFV | 13 |
| 5 | DDI+ 3TC+ RTV+ SQV | 63 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74V, M184V, L210W, T215Y | V21I, V35T, T39A, K43Q, V60I, V118I, K122E, D123N, I135T, K173I, Q174K, D177E, I178M, T200A, Q207E, R211K, I244IV, V245K, D250E, A272P, T286A, E291D, V292I, I293V, E297A, A304E, D324E, I329V |
| >97083| codons 1-333 PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTEICAELEQEGKISKIGPENPYNTPI FAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPEMVI YQYVDDLYVGSDLEIGQHRAKIEELREHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPVKLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTAEAE LELEENREILKEPVHGVYYDPSKELIAEVQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, G48V, I54V, V82T | L10I, I13V, K14R, K20I, E35DN, M36V, R41Q, H69K, K70E, A71V, L89I, I93L |
| >97083| codons 1-98 PQITLWQRPIVTVRIGGQLIEALLDTGADDTVLENVNLPGQWKPKLIVGIGGFVKVRQYD QILIEICGKEVIGTVLVGPTPTNIIGRNILTQLGCTLN |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |