<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PL29021 102123 Portugal 2004 HIV1 F Plasma None

Treatment History
Order Regimen Weeks
1 AZT+ 3TC 139
2 D4T+ DDI+ EFV 215

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74V, T215Y   L100I, K103N   V35KR, K43KQ, K102R, D123E, S162SC, E169D, R172RK, K173A, Q174K, E203EK, Q207E, R211K, K223Q, L228R, V245Q, E248D, A272P, T286A, V292I, I293V, E297AV  
>102123| codons 1-316
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALREICTELEQEGKISKIGPENPYNTPV
FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGIKRNKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILDPFKAKNPDIVI
YQYMDDLYVGSDLEIGQHRTKIKELREHLLKWGFYTPDKKHQQEPPFRWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEIVPLTVEAE
LELAENREILKEPVHG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, G17E, K20R, E35D, M36I, R57K, Q61N, L89M  
>102123| codons 1-99
PQITLWQRPLVTIKVGEQLREALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVKQYD
NILIEICGHKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005