<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PL28244 76856 Portugal 2003 HIV1 G Plasma None

Treatment History
Order Regimen Weeks
1 D4T+ 3TC+ IDV 91
2 D4T+ DDI+ EFV 141

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, L90M L33LI I13V, K20I, E35D, M36I, R41K, L63P, H69K, A71V, L89I  
>76856| codons 1-99
PQITLWQRPLVTVKIGGQLIEALLDTGADDTVIEDINLPGKWKPKMIGGIGGFVKVRQYD
QIPIEICGKKVIGTVLVGPTPVNIIGRNIMTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74LV, L210W, T215Y D67S, T69AG K101P, K103N   E28K, K32E, V35T, K43R, V60I, A98S, V106VI, D121HY, K122E, I135T, K173I, Q174K, D177E, T200A, I202IV, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D320E, D324E, I329V  
>76856| codons 1-333
PISPIETVPVKLKPGMDGPKVKQWPLTKEKIEALTEICTELEREGKISKIGPENPYNTPI
FAIKKKSSGKWRKVVDFRELNKRTQDFWEVQLGIPHPSGLPKNKSITVLDVGDAYFSVPL
YEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPEIVI
YQYMDDLYVGSDLEIGQHRAKVEELRKHLWSWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTAEAE
LELAENREILKEPVHGVYYEPSKELIAEVQKQG

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005