Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL28120 | 100793 | Portugal | 2004 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC+ NVP | 30 |
| 2 | AZT+ 3TC+ ABC | 108 |
| 3 | 3TC+ TDF+ LPV | 39 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46MI, I54V, L76V | L24LI, Q58E | L10I, I13V, K20I, E35D, M36I, R41K, L63P, H69K, V82I, L89M |
| >100793| codons 1-99 PQITLWQRPIVTVKIGGQLIEALIDTGADDTVLEDINLPGKWKPKIIGGIGGFVKVREYD QIPIEICGKKAIGTVVVGPTPINIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, M184V, T215Y | E28K, K32E, V35T, T39A, K43R, E44ED, V60I, A98S, K122E, D123N, I135T, K173IT, Q174K, D177E, T200A, E203ED, Q207K, H208HY, L210LS, R211DGNS, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D324E, I329V |
| >100793| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTKEKIEALTEICAELERDGKISKIGPENPYNTPI FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEIVI YQYVDDLYVGSDLEIGQHRAKIDELRKYLSSWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTAEAE LELAENREILKEPVHGVYYDPSKELIAEVQKQG |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |