Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL27956 | 60622 | Portugal | 2001 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDI | 91 |
| 2 | D4T+ 3TC+ NFV | 113 |
| 3 | D4T+ DDI+ NVP+ IDV+ RTV | 71 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90MR | L10V, T12S, I15V, L19I, K20R, E35D, M36I, R41K, I62IV, L63P, H69K, A71AV, T74S, V77VI, I93L |
| >60622| codons 1-99 PQITLWQRPVVSIKVGGQIREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QVPIEICGKKVIGSVLIGPTPVNIIGRNLRTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, T69D, K70R | K219Q | K103N, Y181C | E6EK, K11E, V35T, T39E, S48T, V60I, K122E, D123N, K166R, K173T, D177E, T200A, Q207E, R211K, D218E, L228LR, V245Q, A272P, K277R, E291D, V292I |
| >60622| codons 1-329 PISPIKTVPVELKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPI FAIKKKNSDRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRTQNPEIVI CQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPEQKHQKEPPFRWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIIPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEI |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |